Hepatitis (plural hepatitides) is a medical condition defined by the inflammation of the liver and characterized by the presence of inflammatory in the tissue of the organ. The name is from the Greek hepar, the root being hepat-, meaning liver, and suffix -itis, meaning "inflammation" The condition can be self-limiting (healing on its own) or can progress to fibrosis (scarring) and cirrhosis.
Hepatitis may occur with limited or no symptoms, but often leads to jaundice, anorexia (poor appetite) and malaise . Hepatitis is acute when it lasts less than six months and chronic when it persists longer. A group of viruses known as the hepatitis viruses cause most cases of hepatitis worldwide, but it can also be due to toxins (notably alcohol , certain medications , some industrial organic solvents and plants), other infections and autoimmune diseases.
Acute Condition
Initial features are of nonspecific flu-like symptoms, common to almost all acute viral infections and may include malaise , muscle and joint pains , fever ,nausea or vomiting, diarrhea , and headache . More specific symptoms , which can be present in acute hepatitis from any cause, are: profound loss of appetite , aversion to smoking among smokers , dark urine ,yellowing of the eyes and skin(i.e.jaundice) and abdominal l discomfort. Physical findings are usually minimal, apart from jaundice in a third and tender hepatomegaly (swelling of the liver) in about 10%. Some exhibit lymphadenopathy (enlarged lymph nodes, in 5%) or splenomegaly (enlargement of the spleen in 5%).
Acute viral hepatitis is more likely to be asymptomatic in younger people. Symptomatic individuals may present after convalescent stage of 7 to 10 days, with the total illness lasting 2 to 6 weeks.
A small proportion of people with acute hepatitis progress to acute liver failure , in which the liver is unable to clear harmful substances from the circulation (leading to confusion and coma due to hepatic encephalopathy) and produce blood proteins (leading to peripheral edema and bleeding). This may become life-threatening and occasionally requires a LIVER TRANSPLANT
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